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This advanced composite formulation features N-trimethyl chitosan coated and doxorubicin loaded liposomes. The structural matrix encapsulates the hydrophilic anthracycline doxorubicin entirely within its central aqueous core via an active remote-loading gradient, utilizing a high-purity phospholipid vesicle core whose exterior polar boundary is enveloped by an electrostatically bound outer layer of the water-soluble, quaternized biopolymer N-trimethyl chitosan. This quaternized biopolymer modification establishes a robust positive surface potential and a dense protective hydration barrier, altering overall membrane bending elasticity to completely prevent physical vesicle aggregation while completely suppressing anthracycline leakage or rapid phase separation under ambient laboratory testing conditions.
Source
Custom synthesis
Functional Group
N-Trimethyl chitosan; Doxorubicin
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Publications
Publications (0)
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Publications
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CD BioGlyco is a leading biotechnology company specializing in glycobiology. We deliver high-quality products and services to support cutting-edge research worldwide.