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N-Trimethyl chitosan (TMc)-coated sparfloxacin nanoliposomes
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Cat. No.: X26-05-ZQ1972

N-Trimethyl chitosan (TMc)-coated sparfloxacin nanoliposomes

Synonym: TMC-coated sparfloxacin nanoliposomes; N-Trimethyl chitosan coated sparfloxacin NLs; TMC-coated sparfloxacin NLs

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Product Size
100 mg; 250 mg; 500 mg; 1 g; 5 g
Price
Datasheet
MSDS
Properties
Description
This advanced composite formulation features N-trimethyl chitosan coated sparfloxacin nanoliposomes (N-Trimethyl chitosan (TMc)-coated sparfloxacin nanoliposomes). The structural framework consists of a high-purity phospholipid sub-micron vesicle core encapsulating the fluorinated compound sparfloxacin, whose exterior boundary is completely enveloped by an electrostatically bound outer layer of the water-soluble quaternized polymer N-trimethyl chitosan (TMc). This surface modification introduces a highly positive surface charge profile and establishes a dense hydrophilic steric layer around the lipid headgroups, which increases membrane thickness and controls the passive crystallization of the fluoroquinolone cargo in open aqueous suspension.
Source
Custom synthesis
Functional Group
N-Trimethyl chitosan; Sparfloxacin
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Publications
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