Lentinan-iodoacetate, called iodoacetate-lentinan, comprises a novel conjugate merging the immunotherapeutic β-1,3-1,6-glucan lentinan with iodoacetate. This composite entity applies lentinan's helical tertiary formation and cancer-restraining capabilities through thymus-oriented immune system stimulation.
Glycan Name
Lentinan
Glycan Structure
Its glycan structure is a β-(1→3)-linked d-glucose backbone with β-(1→6)-glucosyl side branches.
Source
Chemical synthesis
Functional Group
Iodoacetate
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Lentinan-iodoacetate can be used for its potential to explore iodoacetate coupling for thiol-selective protein conjugation during enzyme activity assays.
Publications
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Publications
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