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IRE1 inhibitor, MKC3946, Purity ≥98%
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Cat. No.: X24-08-YM183

IRE1 inhibitor, MKC3946, Purity ≥98%

Synonym: 1093119-54-0; MKC 3946; MKC-3946; 2-Hydroxy-6-(5-(4-methylpiperazine-1-carbonyl)thiophen-2-yl)-1-naphthaldehyde; 2-hydroxy-6-[5-(4-methylpiperazine-1-carbonyl)thiophen-2-yl]naphthalene-1-carbaldehyde; 2-Hydroxy-6-[5-(4-methylpiperazine-1-carbonyl)thiophen-2-yl]naphthalene-1-carbaldehyde

  • CAS Number: 1093119-54-0
  • Compound CID: 59599728
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Product Size
1 mg; 5 mg; 10 mg; 50 mg
Price
Datasheet
MSDS
Properties
Description
MKC3946, soluble in DMSO and ethanol and insoluble in water, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting IRE1.
Molecular Weight
380.46
Molecular Formula
C21H20N2O3S
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 35 mg/mL (91.99 mM); Water: insoluble; Ethanol: 3 mg/mL (7.88 mM)
Applications
MKC3946 is a DNA damage inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of various cancers and autoimmune diseases, as BTK is involved in B-cell signaling pathways.
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