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Irinotecan/JQ1 actively targeted liposomes

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Cat. No.: X26-05-ZQ2848

Irinotecan/JQ1 actively targeted liposomes

Name: Irinotecan/JQ1 actively targeted liposomes
SKU: X26-05-ZQ2848

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Synonym: Irinotecan/JQ1 actively targeted LPs; Irinotecan-JQ1 actively targeted liposomes; Irinotecan/JQ1 actively targeted liposomal nanocarriers

Product Size

100 mg; 250 mg; 500 mg; 1 g; 5 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

This highly advanced multi-functional targeted formulation features ligand-functionalized liposomes co-loaded with irinotecan and a bromodomain inhibitor. The complex structural framework encapsulates the hydrophilic camptothecin derivative irinotecan within its central aqueous core via an active remote-loading gradient, while simultaneously incorporating the hydrophobic thienotriazolodiazepine compound JQ1 within the lipophilic tail regions of its bilayer shell, whose exterior boundary presents a dense target-mimetic affinity ligand array. This intricate configuration coordinates dual-targeted ligand tracking handles with a protective dual-phase multi-cargo boundary, completely preventing drug crystallization, premature chemical hydrolysis, and physical vesicle aggregation under ambient laboratory testing conditions.

Source

Custom synthesis

Functional Group

Target ligand; Irinotecan; JQ1 bromodomain inhibitor

Form

Solid or powder

Purity

≥95%

Impurities

No visible impurities to the naked eye.

Identity

HPLC/MS/NMR

Publications

Publications (0)

Publications

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Publications

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