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Isocitrate dehydrogenase (IDH) inhibitor, Enasidenib, Purity ≥98%
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Cat. No.: X24-09-YM322

Isocitrate dehydrogenase (IDH) inhibitor, Enasidenib, Purity ≥98%

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Synonym: 1446502-11-9; AG-221; AG 221; AG221; 2-Methyl-1-[[4-[6-(trifluoromethyl)pyridin-2-yl]-6-[[2-(trifluoromethyl)pyridin-4-yl]amino]-1,3,5-triazin-2-yl]amino]propan-2-ol; Isocitrate dehydrogenase (IDH) inhibitor

  • MDL: MFCD29472245
  • CAS Number: 1446502-11-9
  • Compound CID: 89683805
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Enasidenib, soluble in DMSO and ethanol and insoluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting isocitrate dehydrogenase (IDH). The molecular weight of the compound is 473.38, and its molecular formula is C19H17F6N7O. It targets the IDH2.
Molecular Weight
473.38
Molecular Formula
C19H17F6N7O
Targets
IDH2
Form
Lyophilized powder
Purity
≥98%
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 90 mg/mL (190.12 mM); Water: insoluble; Ethanol: 90 mg/mL (190.12 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Enasidenib can be used for its ability to restore normal cellular differentiation and reduce the accumulation of oncometabolites associated with IDH2 mutations.
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