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Isocitrate dehydrogenase (IDH) inhibitor, Enasidenib, Purity ≥98%

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Cat. No.: X24-09-YM322

Isocitrate dehydrogenase (IDH) inhibitor, Enasidenib, Purity ≥98%

Synonym: 1446502-11-9; AG-221; AG 221; AG221; 2-Methyl-1-[[4-[6-(trifluoromethyl)pyridin-2-yl]-6-[[2-(trifluoromethyl)pyridin-4-yl]amino]-1,3,5-triazin-2-yl]amino]propan-2-ol; Isocitrate dehydrogenase (IDH) inhibitor

MDL: MFCD29472245
CAS Number: 1446502-11-9
Compound CID: 89683805

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

Enasidenib, soluble in DMSO and ethanol and insoluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting isocitrate dehydrogenase (IDH). The molecular weight of the compound is 473.38, and its molecular formula is C₁₉H₁₇F₆N₇O. It targets the IDH2.

Molecular Weight

473.38

Molecular Formula

C₁₉H₁₇F₆N₇O

Targets

Form

Lyophilized powder

Purity

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 90 mg/mL (190.12 mM); Water: insoluble; Ethanol: 90 mg/mL (190.12 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

Enasidenib can be used for its ability to restore normal cellular differentiation and reduce the accumulation of oncometabolites associated with IDH2 mutations.

Publications

Publications (0)

Publications

Publications

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