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JNK-c-Jun inhibitor SP600125, Purity ≥98%
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Cat. No.: X23-10-ZQ924

JNK-c-Jun inhibitor SP600125, Purity ≥98%

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Synonym: 129-56-6; 1,9-Pyrazoloanthrone; SP600125; Pyrazolanthrone; Dibenzo[cd,g]indazol-6(2H)-one; Pyrazoleanthrone; JNK-c-Jun inhibitor

  • MDL: MFCD00022289
  • CAS Number: 129-56-6
  • Compound CID: 8515
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Product Size
10 mg; 25 mg; 50 mg; 100 mg; 200 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
SP600125, soluble in DMSO and insoluble in ethanol and water, is an inhibitor of c-jun N-terminal kinase (JNK) signaling. It targets Aurora A, Chk1, EGF, and ERK2.
Molecular Weight
220.2
Molecular Formula
C14H8N2O
Targets
Aurora A: 60 nM; Chk1: >10 μM; EGF: >10 μM; ERK2: >10 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 43 mg/mL (195.25 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
SP600125 is utilized to study the inhibition of JNK (c-Jun N-terminal kinase) and its effects on apoptosis, inflammation, and cancer.
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