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Cat. No.: X26-02-ZQ4720

Kdo2-lipid A

Synonym: (2R,5R)-2-[(2R,4R,5R)-2-carboxy-6-[(1R)-1,2-dihydroxyethyl]-2-[[(3S,5S,6R)-5-[[(3R)-3-dodecanoyloxytetradecanoyl]amino]-6-[[(3S,5S,6R)-3-hydroxy-5-[[(3R)-3-hydroxytetradecanoyl]amino]-4-[(3R)-3-hydroxytetradecanoyl]oxy-6-phosphonooxyoxan-2-yl]methoxy]-3-phosphonooxy-4-[(3R)-3-tetradecanoyloxytetradecanoyl]oxyoxan-2-yl]methoxy]-5-hydroxyoxan-4-yl]oxy-6-[(1R)-1,2-dihydroxyethyl]-4,5-dihydroxyoxane-2-carboxylic acid

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Product Size
1 mg; 10 mg; 25 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
Consisting of Lipid A linked to two KDO residues, this molecule is the minimal lipopolysaccharide (LPS) unit required for bacterial viability. It is a chemically defined ligand used for high-precision studies of TLR4 dimerization and signaling.
Molecular Weight
2238.7
Molecular Formula
C110H202N2O39P2
Source
Chemical synthesis
Form
Solid or liquid
Purity
≥90%
Identity
Confirmed by NMR/HPLC/MS.
Applications
Kdo2-lipid A can be used as a chemically defined agonist to study the minimal structural unit required for full TLR4/MD2 activation.
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