Inquiry
Cat. No.: X23-10-ZQ602
Keap1-Nrf2 inhibitor RTA-408, Purity ≥98%
Synonym: Omaveloxolone; 1474034-05-3; RTA-408; RTA 408; Nrf1-activator-1; SKYCLARYS; Keap1-Nrf2 inhibitor
- MDL: MFCD28167769
- CAS Number: 1474034-05-3
- Compound CID: 71811910
Properties
Description
RTA-408, soluble in DMSO and ethanol and insoluble in water, is an active small molecule compound that mediates the Keap1-Nrf2 signaling pathway. It targets Nrf2.
Molecular Weight
554.71
Molecular Formula
C33H44F2N2O3
Targets
Nrf2
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 98 mg/mL (176.66 mM); Water: Insoluble; Ethanol: 20 mg/mL (36.05 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
RTA-408 can be leveraged in research looking at its potential as an activator of Nrf2 in oxidative stress and inflammatory diseases.
Publications
Publications (0)

×
Publications
Thank you for choosing our products for your research. By sharing your publications or experimental feedback, you provide invaluable insights that help fellow scientists accelerate their discoveries. Your contribution also drives our commitment to continuous product optimization.
As a token of our appreciation, verified submissions will receive an exclusive discount code for your next order.
*Submitted research data and images may be featured on our product pages. We strictly protect your personal privacy; no sensitive contact information will ever be disclosed.
Related Products
- Keap1-Nrf2 inhibitor Nrf2-IN-1, Purity ≥98%
- Keap1-Nrf2 inhibitor Oltipraz, Purity ≥98%
- Keap1-Nrf2 inhibitor NK-252, Purity ≥98%
- Keap1-Nrf2 inhibitor ML-385, Purity ≥98%
Quick Links
PRODUCTS
- Hot Glycans
- Featured Products
- Carbohydrates
- Nucleosides and Nucleotides
- Enzymes
- Lectin Products
- Carbohydrate Antigen
- Glycoconjugates
- Assay Kits
- Glycosylation Related Products
- Natural Products
- Inhibitors
- Protein Tyrosine Kinases
- TGF-β-Smad
- Cell Cycle
- Neuronal Signaling
- Proteases
- Cell Metabolism
- Endocrinology-Hormones
- GPCR-G Protein
- Adrenergic Receptor
- Histamine Receptor
- mGluR
- 5-HT Receptor
- Adenosine Receptor
- Dopamine Receptor
- Neurokinin Receptor
- Calcium-sensing Receptor
- S1P Receptor
- Platelet-activating Factor (PAF) Receptor
- LPA Receptor
- Smoothened Receptor
- Opioid Receptor
- Melatonin Receptor
- CGRP Receptor
- Endothelin Receptor
- Prostanoid Receptor
- Cannabinoid Receptor
- Glucagon Receptor
- G Protein
- Guanylate Cyclase
- Orexin Receptor
- Imidazoline Receptor
- Neurotensin Receptor
- Peptide Receptor
- CCK
- NPY Receptor
- MCHR1 (GPR24)
- Sigma Receptor
- GHSR
- GPCR19
- Formyl Peptide Receptor (FPR)
- Angiotensin Receptors
- GLP-1 receptors
- Rev-Erb Receptors
- CRFR
- Vasopressin Receptor
- Protease-Activated Receptors (PAR)
- Oxytocin Receptor
- Bradykinin Receptor
- Adenylyl Cyclase
- Urotensin Receptor
- Somatostatin Receptors
- Bombesin Receptor
- cAMP
- CXCR
- Leukotriene Receptor
- Membrane Transporters-Ion Channels
- AMPA Receptor
- Sodium Channel
- Calcium Channel
- SGLT
- ATPase
- Proton Pump
- Potassium Channel
- P-gp
- CFTR
- Chloride Channels
- TRPV
- Monocarboxylate Transporters (MCT)
- HCN Channel
- NCX
- TRP Channel
- Na+-H+ Exchanger
- OCT
- Glutamate (EAAT) Transporter
- Serotonin Transporter
- BCRP
- VDAC
- Aquaporin
- Piezo Channel
- Monoamine Transporter
- CRM1
- Transferases
- Stem Cells-Wnt
- Autophagy Signaling
- Metabolism
- MAO
- PPAR
- FXR
- Cytochrome P450
- PDE
- HSP
- Hydroxylase
- Factor Xa
- DHFR
- Dehydrogenases
- Procollagen C-proteinase
- Carbonic Anhydrase
- LXR
- FAAH
- 15-PGDH
- CETP
- Ferroptosis
- HMG-CoA Reductase
- Isocitrate Dehydrogenase (IDH)
- IDO
- Retinoid Receptor
- Lipase
- Phospholipase
- Lipoxygenase
- AhR
- NAMPT
- GLUT
- Antimetabolite
- Hexokinase
- Epoxide Hydrolase
- Stearoyl-CoA Desaturase (SCD)
- Lipid Metabolism
- Neuronal Metabolism
- SREBP
- LDL
- Foxo1
- DGAT
- Farnesyl Transferase
- Thioredoxin
- Vitamin
- Decarboxylase
- ACLY
- Fatty Acid Synthase (FASN)
- Glucokinase
- Lactate Dehydrogenase A (LDHA)
- Oxidative Phosphorylation
- PFKFB3
- Ribonucleotide Reductase
- Acetyl-CoA Carboxylase
- Glucosidase
- PAI-1
- Immunology & Inflammation
- PI3K/Akt/mTOR
- Angiogenesis
- Apoptosis
- DNA Damage
- Epigenetics
- JAK/Stat
- MAPK
- Microbiology
- NF-kB/IkB
- Stem Cells/Wnt
- DNA-RNA Synthesis
- Cytoskeletal Signaling
- Ubiquitin
- Other inhibitors
- PROTAC
- Bioactive Compounds
- Glycobiology Arrays
- Glycolipids
- Nanomaterials
GalNAc-L96 intermediate, T1 (Cat#: X24-11-YM010)
GalNAc-L96 intermediate, T2 (Cat#: X24-11-YM011)
GalNAc-L96 intermediate, T3 (Cat#: X24-11-YM012)
GalNAc-L96 intermediate, T4-Amine (Cat#: X24-11-YM014)
Tri-GalNAc(OAc)3 Cbz (Cat#: X24-11-YM015)
Tri-GalNAc(OAc)3 (Cat#: X24-11-YM016)
Tri-GalNAc(OAc)3 TFA (Cat#: X24-11-YM017)
GalNAc-L96-OH (Cat#: X24-11-YM018)
GalNAc-L96-TEA (Cat#: X24-11-YM019)
Neu5Gcα(2-6)N-Glycan (Cat#: X23-03-YW036)
A2G2 N-Glycan (Cat#: X23-03-YW037)
A2G2S2 N-Glycan (Cat#: X23-03-YW038)
A2 N-Glycan (Cat#: X23-03-YW039)
A2[6]G1 N-Glycan (Cat#: X23-03-YW040)
M3 N-Glycan (Cat#: X23-03-YW041)
A2[3]G2S1 N-Glycan (Cat#: X23-03-YW042)
Core 2 O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW178)
Core 2 O-glycan, Thr-Fmoc linked (Cat#: X23-10-YW179)
Core 3 O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW180)
Core 3 O-glycan, Thr-Fmoc linked (Cat#: X23-10-YW181)
Core 4 O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW182)
T antigen O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW192)
T antigen O-glycan, Thr-Fmoc linked (Cat#: X23-10-YW193)
Tn antigen O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW194)
Blood group A trisaccharide (Cat#: XCO0060Q)
Blood group B trisaccharide (Cat#: XCO0068Q)
Blood group H disaccharide (Cat#: XCO0074Q)
Lewis A trisaccharide (Cat#: XCO0079Q)
3'-Sulfated lewis A (Cat#: XCO0080Q)
Lewis B tetrasaccharide (Cat#: XCO0083Q)
Lewis X trisaccharide (Cat#: XCO0085Q)
Lewis Y tetrasaccharide (Cat#: XCO0088Q)
Lacto-N-biose (Cat#: XCO0089Q)
2'-Fucosyllactose (Cat#: XCO0091Q)
3-Fucosyllactose (Cat#: XCO0092Q)
Lactodifucotetraose (Cat#: XCO0093Q)
Lacto-N-triose I (Cat#: XCO0094Q)
3'-Sialyllactose sodium salt (Cat#: XCO0096Q)
6'-Sialyllactose sodium salt (Cat#: XCO0098Q)
3'-Sialyl-3-fucosyllactose (Cat#: XCO0100Q)
Heparin amine, MW 27 kDa (Cat#: X22-09-ZQ478)
FITC-heparin, MW 27 kDa (Cat#: X22-09-ZQ480)
TRITC-heparin, MW 27 kDa (Cat#: X22-09-ZQ481)
Biotin-heparin-FITC, MW 18 kDa (Cat#: X22-09-ZQ482)
Chondroitin sulfate (dp4) (Cat#: X22-11-ZQ598)
Dermatan sulfate (dp12) (Cat#: X22-11-ZQ611)
Heparin disaccharide I-A (Cat#: X22-11-ZQ662)
Chondroitine sulfate (Cat#: X23-04-XQ1118)
GalNAcβ(1-4)GlcNAcβ-Sp3-Biotin (Cat#: X22-12-ZQ005)
GalNAcβ(1-4)GlcNAcβ-Sp3-PAA-Biotin (Cat#: X22-12-ZQ006)
GalNAcβ(1-4)GlcNAcβ-Sp3-PAA-FITC (Cat#: X22-12-ZQ007)
GalNAcβ(1-4)GlcNAcβ-Sp3-PAA (Cat#: X22-12-ZQ008)
Glcβ(1-4)GalNAcα-Sp3-Biotin (Cat#: X22-12-ZQ037)
Glcβ(1-4)GalNAcα-Sp3-PAA-Biotin (Cat#: X22-12-ZQ038)
Glcβ(1-4)GalNAcα-Sp3-PAA-FITC (Cat#: X22-12-ZQ039)
Glcβ(1-4)GalNAcα-Sp3-PAA (Cat#: X22-12-ZQ040)
GlcCer (d18:1/8:0) (Cat#: X23-11-ZQ101)
GalCer (d18:1/16:0) (Cat#: X23-11-ZQ112)
LacCer (d18:1/8:0) (Cat#: X23-11-ZQ118)
Lc3Cer (d18:1/8:0) (Cat#: X23-11-ZQ131)
Lc4Cer (d18:1/12:0) (Cat#: X23-11-ZQ146)
Sialyl-Lc4Cer (d18:1/18:0) (Cat#: X23-11-ZQ162)
Lewis a Cer (d18:1/16:0) (Cat#: X23-11-ZQ175)
nLc4Cer (d18:1/18:0) (Cat#: X23-11-ZQ190)
Methyl-γ-cyclodextrin (DS 12) (Cat#: X23-11-YM119)
Carboxymethyl-ɑ-cyclodextrin sodium salt (Cat#: X23-11-B003)
Carboxymethyl-γ-cyclodextrin sodium salt (Cat#: X23-11-B004)
Succinyl-ɑ-cyclodextrin (Cat#: X23-11-B005)
Succinyl-γ-cyclodextrin (Cat#: X23-11-B006)
ɑ-Cyclodextrin sulfate sodium salt (Cat#: X23-11-B007)
β-Cyclodextrin sulfate sodium salt (Cat#: X23-11-B008)
γ-Cyclodextrin sulfate sodium salt (Cat#: X23-11-B009)
Lysine-dextran, MW 4 kDa (Cat#: X22-09-ZQ273)
Phenyl-dextran, MW 150 kDa (Cat#: X22-09-ZQ279)
FITC-Q-dextran, MW 10 kDa (Cat#: X22-09-ZQ280)
FITC-lysine-dextran, MW 10 kDa (Cat#: X22-09-ZQ283)
TRITC-lysine-dextran, MW 10 kDa (Cat#: X22-09-ZQ287)
FITC-dextran sulfate, MW 10 kDa (Cat#: X22-09-ZQ291)
Dextran amine, MW 20 kDa (Cat#: X22-09-ZQ377)
TRITC-dextran, MW 40 kDa (Cat#: X22-09-ZQ383)
Biotin-dextran-FITC, MW 20 kDa (Cat#: X22-09-ZQ389)
Online Inquiry


