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Ketanserin
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Cat. No.: X23-12-YM458

Ketanserin

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Synonym: 74050-98-9; R 41468

  • CAS Number: 74050-98-9
  • PubChem CID: 3822
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Product Size
50 mg; 100 mg; 250 mg; 500 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Ketanserin (vulketan gel), soluble in DMSO and insoluble in water and ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT2A, 5-HT2C (human), and 5-HT2C (rat).
Molecular Weight
395.43
Molecular Formula
C22H22FN3O3
Targets
5-HT2A: 2.5 nM (Ki); 5-HT2C (Human): 100 nM (Ki); 5-HT2C (Rat): 50 nM (Ki)
Form
Lyophilized powder
Purity
>98%
Solubility
DMSO: 2 mg/mL (5.05 mM); Water: insoluble; Ethanol: insoluble
Applications
Ketanserin (vulketan gel) can be used as a selective serotonin receptor antagonist (specifically targeting the 5-HT2A receptor subtype), leading to vasodilation and lowering of blood pressure.
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