Lentinan-lipoic acid, referred to as lipoic acid-lentinan, represents a modern bioconjugate coupling the immunomodulatory β-1,3-1,6-glucan lentinan with lipoic acid. This engineered compound leverages lentinan's three-strand helical geometry and malignancy-inhibiting characteristics through thymus-dependent immune response mechanisms.
Glycan Name
Lentinan
Glycan Structure
Its glycan structure is a β-(1→3)-linked d-glucose backbone with β-(1→6)-glucosyl side branches.
Source
Chemical synthesis
Functional Group
Lipoic acid
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Lentinan-lipoic acid can be used for its potential to integrate lipoic acid moieties to create redox-responsive nanoparticles for glutathione-triggered drug release.
Publications
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Publications
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