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LXR inhibitor, GW3965 HCl, Purity ≥98%
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Cat. No.: X24-09-YM241

LXR inhibitor, GW3965 HCl, Purity ≥98%

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Synonym: 405911-17-3; GW-3965; GW3965 hydrochloride; 2-[3-[3-[[2-Chloro-3-(trifluoromethyl)phenyl]methyl-(2,2-diphenylethyl)amino]propoxy]phenyl]acetic acid; hydrochloride; LXR inhibitor

  • MDL: MFCD08276920
  • CAS Number: 405911-17-3
  • Compound CID: 16078973
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
GW3965 HCl, soluble in DMSO and insoluble in water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting LXR. The molecular weight of the compound is 618.51, and its molecular formula is C33H31ClF3NO3·HCl. It targets the hLXRα (Cell-free assay), hLXRβ (Cell-free assay), and LXRα/SRC1LiSA (Cell-free assay).
Molecular Weight
618.51
Molecular Formula
C33H31ClF3NO3·HCl
Targets
hLXRα (Cell-free assay)
Form
Lyophilized powder
Purity
≥98%
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO (warmed): 16 mg/mL (25.86 mM); Water: insoluble; Ethanol: insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
GW3965 HCl can be studied extensively for its potential therapeutic applications in the treatment of dyslipidemia and atherosclerosis.
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