Properties
Description
Lentinan-maleimide, known as MAL-lentinan, stands as an innovative conjugate merging the immune-modulating β-1,3-1,6-glucan lentinan with MAL. The composite design employs lentinan's triplex helical formation and neoplasm-restraining capabilities via thymus-dependent immunological response activation.
Glycan Structure
Its glycan structure is a β-(1→3)-linked d-glucose backbone with β-(1→6)-glucosyl side branches.
Source
Chemical synthesis
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Lentinan-maleimide can be used for its potential to utilize maleimide chemistry for site-specific antibody conjugation in bispecific therapeutic platforms.