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MDM2 antagonist Nutlin-3, Purity ≥98%
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Cat. No.: X23-10-ZQ121

MDM2 antagonist Nutlin-3, Purity ≥98%

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Synonym: 548472-68-0; 890090-75-2; Nutlin-3; Nutlin 3; (Rac)-Nutlin-3; 4-(4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)piperazin-2-one; MDM2 antagonist

  • MDL: MFCD14636430; MFCD07784509; MFCD11977784
  • CAS Number: 548472-68-0
  • Compound CID: 216345
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Nutlin-3, soluble in DMSO and ethanol and insoluble in water, is an active small molecule compound that mediates the MDM2 signaling pathway.
Molecular Weight
581.5
Molecular Formula
C30H30Cl2N4O4
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 87 mg/mL (149.61 mM); Water: Insoluble; Ethanol: 26 mg/mL (44.71 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Nutlin-3 is studied for its ability to inhibit the interaction between p53 and MDM2, thereby stabilizing p53 and inducing apoptosis in cancer cells.
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