Metronidazole-xylan conjugation establishes an antimicrobial hybrid system combining nitroimidazole properties with xylan's β-1,4-linked xylose matrix from plant biomass. The carbohydrate architecture contributes to enhanced aqueous dispersibility.
Glycan Name
Xylan
Glycan Structure
Its glycan structure is a linear backbone of β-1,4-linked D-xylose residues with side-chain substitutions including α-linked arabinofuranose, glucuronic acid/4-O-methyl-glucuronic acid, and acetyl groups at O-2 or O-3 positions.
Source
Chemical synthesis
Functional Group
Metronidazole
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Xylan-metronidazole can be used for its potential to optimize nanoparticle self-assembly via tyrosine-mediated π-π stacking interactions.
Publications
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Publications
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