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Miriplatin and nucleic acid miR-34a co-loaded cationic liposomes
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Cat. No.: X26-05-ZQ2046

Miriplatin and nucleic acid miR-34a co-loaded cationic liposomes

Synonym: Miriplatin/miR-34a co-loaded cationic liposomes; Miriplatin-miR-34a co-delivered cationic LPs; Miriplatin/miR-34a cationic lipoplexes

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Product Size
100 mg; 250 mg; 500 mg; 1 g; 5 g
Price
Datasheet
MSDS
Properties
Description
This highly complex dual-cargo formulation features miriplatin and microRNA-34a co-loaded cationic liposomes. The structural framework incorporates a combined hydrophobic and hydrophilic regimen, embedding the lipophilic organoplatinum coordination complex miriplatin directly within the hydrocarbon core of a phospholipid bilayer while electrostatically condensing microRNA-34a (miR-34a) fragments onto its cationic lipid surface. This advanced multi-loading configuration coordinates the positive charge density of the headgroups to protect the nucleic acid strands from premature degradation, while preventing competitive phase separation of the platinum cargo in open laboratory media.
Source
Custom synthesis
Functional Group
Miriplatin; miR-34a; Cationic lipid
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Publications
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