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Cat. No.: X26-06-ZQ218

Mitomycin-phospholipid complex-loaded PLA nanoparticles

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Synonym: Mitomycin-phospholipid-PLA NPs; Mitomycin-lipid complex-loaded PLA nanoparticles; Mitomycin-phospholipid complexed polylactic acid nanocarriers

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Product Size
100 mg; 250 mg; 500 mg; 1 g; 5 g
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
These mitomycin-phospholipid complex-loaded PLA nanoparticles feature a lipophilic drug-lipid complex dispersed inside a biodegradable polylactic acid (PLA) polymer matrix. The composition relies on the amphiphilic properties of the pre-formed phospholipid complex to enhance the structural compatibility between the hydrophilic quinone drug and the hydrophobic polyester carrier. It displays high encapsulation parameters and a markedly reduced initial surface leaching burst during fluid extraction testing.
Source
Custom synthesis
Functional Group
Mitomycin; Phospholipid
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Applications
This product can be used to study drug-lipid complexation thermodynamics, investigate solute mass transfer across aliphatic polyester networks, and analyze formulation encapsulation physics.
Publications
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