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Mitoxantrone hydrochloride long-circulating thermosensitive liposomes

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Cat. No.: X26-05-ZQ2863

Mitoxantrone hydrochloride long-circulating thermosensitive liposomes

Name: Mitoxantrone hydrochloride long-circulating thermosensitive liposomes
SKU: X26-05-ZQ2863

Inquiry

Synonym: Mitoxantrone HCl stealth TSLs; Mitoxantrone hydrochloride long-circulating thermosensitive liposomes; Mitoxantrone HCl pegylated thermosensitive LPs

Product Size

100 mg; 250 mg; 500 mg; 1 g; 5 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

This highly advanced responsive steric material features mitoxantrone hydrochloride loaded long-circulating thermosensitive liposomes. The intricate structural framework incorporates a phase-transition lipid base composed primarily of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine designed to undergo a sharp melting transition at a specific thermal threshold (41ºC), encapsulating the hydrophilic anthracenedione compound mitoxantrone hydrochloride entirely within its central aqueous core via an active remote-loading gradient, while its exterior boundary is surface-modified with dense polyethylene glycol polymer brushes. This complex layout couples a thermally triggered release mechanism with a dense protective hydrophilic steric brush layer, completely preventing physical vesicle aggregation and restricting passive drug leakage under baseline laboratory calibration indices.

Source

Custom synthesis

Functional Group

Mitoxantrone hydrochloride; Thermosensitive matrix

Form

Solid or powder

Purity

≥95%

Impurities

No visible impurities to the naked eye.

Identity

HPLC/MS/NMR

Publications

Publications (0)

Publications

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Publications

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