Cat. No.: X24-07-ZQ754
MMP inhibitor GM 6001, Purity ≥98%
Synonym: 142880-36-2; MMP inhibitor; Galardin; Ilomastat; GM-6001
- MDL: MFCD00917040
- CAS Number: 142880-36-2
- Compound CID: 132519
Product Size
10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
GM 6001, soluble in DMSO and warmed ethanol and insoluble in water, inhibits MMPs, enzymes that degrade extracellular matrix components, thus having potential therapeutic applications in cancer and chronic inflammatory diseases. It targets MMP-26, MMP-9, MMP-1, MMP-12, MMP-14, MMP-2, MMP-3, MMP-7, and MMP-8.
Molecular Formula
C20H28N4O4
Targets
MMP-26: 0.36 nM (Ki); MMP-9: 0.2 nM (Ki); MMP-1: 0.4 nM (Ki); MMP-12: 3.6 nM (Ki); MMP-14: 13.4 nM (Ki); MMP-2: 0.5 nM (Ki); MMP-3: 27 nM (Ki); MMP-7: 3.7 nM (Ki); MMP-8: 0.1 nM (Ki)
Solubility
DMSO: 73 mg/mL (187.92 mM); Water: Insoluble; Warmed ethanol: 7 mg/mL (18.02 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
GM 6001 is an MMP inhibitor used to explore the inhibition of matrix metalloproteinases, significant in cancer metastasis and arthritis research.
Related Products
Quick Links
