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MMP inhibitor GM 6001, Purity ≥98%
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Cat. No.: X24-07-ZQ754

MMP inhibitor GM 6001, Purity ≥98%

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Synonym: 142880-36-2; MMP inhibitor; Galardin; Ilomastat; GM-6001

  • MDL: MFCD00917040
  • CAS Number: 142880-36-2
  • Compound CID: 132519
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
GM 6001, soluble in DMSO and warmed ethanol and insoluble in water, inhibits MMPs, enzymes that degrade extracellular matrix components, thus having potential therapeutic applications in cancer and chronic inflammatory diseases. It targets MMP-26, MMP-9, MMP-1, MMP-12, MMP-14, MMP-2, MMP-3, MMP-7, and MMP-8.
Molecular Weight
388.5
Molecular Formula
C20H28N4O4
Targets
MMP-26: 0.36 nM (Ki); MMP-9: 0.2 nM (Ki); MMP-1: 0.4 nM (Ki); MMP-12: 3.6 nM (Ki); MMP-14: 13.4 nM (Ki); MMP-2: 0.5 nM (Ki); MMP-3: 27 nM (Ki); MMP-7: 3.7 nM (Ki); MMP-8: 0.1 nM (Ki)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 73 mg/mL (187.92 mM); Water: Insoluble; Warmed ethanol: 7 mg/mL (18.02 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
GM 6001 is an MMP inhibitor used to explore the inhibition of matrix metalloproteinases, significant in cancer metastasis and arthritis research.
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