Properties
Description
JNJ0966, soluble in DMSO and insoluble in ethanol and water, inhibits MMPs, enzymes that degrade extracellular matrix components, thus having potential therapeutic applications in cancer and chronic inflammatory diseases.
Molecular Formula
C16H16N4O2S2
Solubility
DMSO: 65 mg/mL (180.33 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
JNJ0966 is explored to block matrix metalloproteinases, involved in degrading extracellular matrix components, critical in cancer, and inflammatory diseases.