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mTOR inhibitor AZD8055, Purity ≥98%
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Cat. No.: X24-05-ZQ004

mTOR inhibitor AZD8055, Purity ≥98%

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Synonym: 1009298-09-2; AZD-8055; AZD 8055; (5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol; mTOR inhibitor

  • CAS Number: 1009298-09-2
  • Compound CID: 25262965
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AZD8055, soluble in warmed DMSO and ethanol and insoluble in water, disrupts cell growth, proliferation, and survival by targeting a key component of cellular signaling pathways. It targets DNA-PK, mTOR(fulllength), ATM, mTOR (truncated), PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.
Molecular Weight
465.5
Molecular Formula
C25H31N5O4
Targets
DNA-PK: 1370 nM; mTOR(fulllength): 0.8 nM; ATM: 1370 nM; mTOR (truncated): 0.13 nM; PI3Kα: 3590 nM; PI3Kβ: 18900 nM; PI3Kδ: 3200 nM; PI3Kγ: >14790 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 49 mg/mL (105.25 mM); Water: Insoluble; Ethanol: 3 mg/mL (6.44 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
AZD8055 can be used to study the inhibition of both mTORC1 and mTORC2 in various cellular processes, including cancer progression.
Publications
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