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MTX agent, Lentinan-PEG-methotrexate, Purity ≥95%
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Cat. No.: X25-05-YM731

MTX agent, Lentinan-PEG-methotrexate, Purity ≥95%

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Synonym: Lentinan-PEG-methotrexate; Methotrexate-PEG-Lentinan

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Product Size
100 mg; 250 mg; 500 mg; 1 g; 5 g
Price
Datasheet
Datasheet
MSDS
MSDS
Sub Cat. No. Molecular Weight Glycan Name Functional Group Inquiry
X25-05-YM731-1 PEG 350 Da Lentinan MTX Inquiry
X25-05-YM731-2 PEG 550 Da Lentinan MTX Inquiry
X25-05-YM731-3 PEG 750 Da Lentinan MTX Inquiry
X25-05-YM731-4 PEG 1 kDa Lentinan MTX Inquiry
X25-05-YM731-5 PEG 2 kDa Lentinan MTX Inquiry
X25-05-YM731-6 PEG 3 kDa Lentinan MTX Inquiry
X25-05-YM731-7 PEG 4 kDa Lentinan MTX Inquiry
X25-05-YM731-8 PEG 5 kDa Lentinan MTX Inquiry
X25-05-YM731-9 PEG 10 kDa Lentinan MTX Inquiry
X25-05-YM731-10 PEG 20 kDa Lentinan MTX Inquiry
Properties
Description
Lentinan-PEG-methotrexate, designated as methotrexate-lentinan, describes a drug-polymer hybrid formed by conjugating methotrexate to lentinan's β-glucan through PEG spacers. This therapeutic system combines chemotherapeutic delivery with lentinan's immunomodulation and DPPS fusogenicity.
Glycan Structure
Its glycan structure is a β-(1→3)-linked d-glucose backbone with β-(1→6)-glucosyl side branches.
Source
Chemical synthesis
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Lentinan-PEG-methotrexate can be used for its potential to evaluate methotrexate loading efficiency in folate antagonist combination therapy models.
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