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Naftopidil

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Cat. No.: X23-12-YM469

Naftopidil

Synonym: 57149-07-2; KT-611; BM-15275

CAS Number: 57149-07-2
PubChem CID: 4418

Product Size

250 mg; 500 mg; 750 mg; 1 g

Price

Datasheet

MSDS

Properties

Description

Naftopidil (flivas), soluble in DMSO and insoluble in water and ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets α1A-adrenergic receptor, α1B-adrenergic receptor, and α1D-adrenergic receptor.

Molecular Weight

392.5

Molecular Formula

C₂₄H₂₈N₂O₃

Targets

α1A-adrenergic receptor: 3.7 nM (Ki); α1B-adrenergic receptor: 20 nM (Ki); α1D-adrenergic receptor: 1.2 nM (Ki)

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 77 mg/mL (196.17 mM); Water: insoluble; Ethanol: insoluble

Applications

Naftopidil (flivas) can be used for its effect on relaxing the smooth muscle in the prostate gland and the bladder neck.

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