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Cat. No.: X24-07-ZQ865
NEDD8-activating enzyme (NAE) inhibitor TAS4464, Purity ≥98%
Synonym: 1848959-10-3; NEDD8-activating enzyme (NAE) inhibitor; TAS4464; TAS-4464; TAS 4464
- CAS Number: 1848959-10-3
- Compound CID: 124121703
Properties
Description
TAS4464, soluble in DMSO and insoluble in ethanol and water, interferes with the activation of the NEDD8-activating enzyme, potentially disrupting processes like protein degradation in cancer cells.
Molecular Weight
506.5
Molecular Formula
C21H23FN6O6S
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 90 mg/mL (177.68 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
TAS4464 is used to inhibit NAE, affecting protein degradation pathways, investigated for cancer therapeutics.
Publications
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