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NEDD8-activating enzyme (NAE) inhibitor TAS4464, Purity ≥98%

Cat. No.: X24-07-ZQ865

NEDD8-activating enzyme (NAE) inhibitor TAS4464, Purity ≥98%

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Synonym: 1848959-10-3; NEDD8-activating enzyme (NAE) inhibitor; TAS4464; TAS-4464; TAS 4464

  • CAS Number: 1848959-10-3
  • Compound CID: 124121703
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Product Size
5 mg; 10 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
TAS4464, soluble in DMSO and insoluble in ethanol and water, interferes with the activation of the NEDD8-activating enzyme, potentially disrupting processes like protein degradation in cancer cells.
Molecular Weight
506.5
Molecular Formula
C21H23FN6O6S
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 90 mg/mL (177.68 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
TAS4464 is used to inhibit NAE, affecting protein degradation pathways, investigated for cancer therapeutics.
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O-Glycan
Core 2 O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW178) Core 2 O-glycan, Thr-Fmoc linked (Cat#: X23-10-YW179) Core 3 O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW180) Core 3 O-glycan, Thr-Fmoc linked (Cat#: X23-10-YW181) Core 4 O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW182) T antigen O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW192) T antigen O-glycan, Thr-Fmoc linked (Cat#: X23-10-YW193) Tn antigen O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW194)
Blood Group and Lewis Antigen
Blood group A trisaccharide (Cat#: XCO0060Q) Blood group B trisaccharide (Cat#: XCO0068Q) Blood group H disaccharide (Cat#: XCO0074Q) Lewis A trisaccharide (Cat#: XCO0079Q) 3'-Sulfated lewis A (Cat#: XCO0080Q) Lewis B tetrasaccharide (Cat#: XCO0083Q) Lewis X trisaccharide (Cat#: XCO0085Q) Lewis Y tetrasaccharide (Cat#: XCO0088Q)
Human Milk Oligosaccharides (HMOs)
Lacto-N-biose (Cat#: XCO0089Q) 2'-Fucosyllactose (Cat#: XCO0091Q) 3-Fucosyllactose (Cat#: XCO0092Q) Lactodifucotetraose (Cat#: XCO0093Q) Lacto-N-triose I (Cat#: XCO0094Q) 3'-Sialyllactose sodium salt (Cat#: XCO0096Q) 6'-Sialyllactose sodium salt (Cat#: XCO0098Q) 3'-Sialyl-3-fucosyllactose (Cat#: XCO0100Q)
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Cyclodextrin
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Dextran
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