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Cat. No.: X26-03-YM1649

Neu5Gc(α2-8)Neu5Gc(α2-3/6)Gal(β1-4)GlcNAc(β1-2)Man(α1-3)[GlcNAc(β1-4)][Man(α1-6)]Man(β1-4)GlcNAc(β1-4)GlcNAc, Purity ≥95%

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Synonym: Neu5Gc(alpha2-8)Neu5Gc(alpha2-3/6)Gal(beta1-4)GlcNAc(beta1-2)Man(alpha1-3)[GlcNAc(beta1-4)][Man(alpha1-6)]Man(beta1-4)GlcNAc(beta1-4)GlcNAc

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Product Size
10 mg; 20 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Neu5Gc(α2-8)Neu5Gc(α2-3/6)Gal(β1-4)GlcNAc(β1-2)Man(α1-3)[GlcNAc(β1-4)][Man(α1-6)]Man(β1-4)GlcNAc(β1-4)GlcNAc is a complex N-glycan featuring a disialic acid motif. The non-reducing end carries two alpha-2,8-linked N-glycolylneuraminic acid residues. The structure includes a bisecting GlcNAc and a standard trimannosyl-chitobiose core without fucose, representing a specialized acidic glycoform.
WURCS
2.0/6,10,9/[u2122h_2*NCC/3=O][a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5][a1122h-1a_1-5][a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCCO/3=O]/1-2-3-4-2-5-6-6-2-4/a4-b1_b4-c1_c3-d1_c4-i1_c6-j1_d2-e1_e4-f1_g8-h2_g2-f3|f6
Motif name
N-Glycan core basic:G00026MO,N-acetyllactosamine:G00055MO,Type 2 LN:G00055MO
Source
Chemical synthesis
Form
Solid
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
Confirmed by NMR.
Applications
Neu5Gc(α2-8)Neu5Gc(α2-3/6)Gal(β1-4)GlcNAc(β1-2)Man(α1-3)[GlcNAc(β1-4)][Man(α1-6)]Man(β1-4)GlcNAc(β1-4)GlcNAc can be used for its potential to provide a massive, bisected and sialylated N-glycan for studying the impact of high-density sialylation on protein stability and function.
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Lacto-N-biose (Cat#: XCO0089Q) 2'-Fucosyllactose (Cat#: XCO0091Q) 3-Fucosyllactose (Cat#: XCO0092Q) Lactodifucotetraose (Cat#: XCO0093Q) Lacto-N-triose I (Cat#: XCO0094Q) 3'-Sialyllactose sodium salt (Cat#: XCO0096Q) 6'-Sialyllactose sodium salt (Cat#: XCO0098Q) 3'-Sialyl-3-fucosyllactose (Cat#: XCO0100Q)
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