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NGR-modified zoledronic acid long-circulating liposomes (NGR-PEG-ZOL LPs)
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Cat. No.: X26-05-ZQ1650

NGR-modified zoledronic acid long-circulating liposomes (NGR-PEG-ZOL LPs)

Synonym: NGR-modified zoledronic acid stealth LPs; NGR-PEG-ZOL stealth liposomes; NGR-PEG-ZOL LPs

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Product Size
100 mg; 250 mg; 500 mg; 1 g; 5 g
Price
Datasheet
MSDS
Properties
Description
This formulation features asparagine-glycine-arginine peptide-modified zoledronic acid long-circulating liposomes (NGR-PEG-ZOL LPs) engineered with a sterically stabilized affinity surface. The vesicular structure encapsulates the hydrophilic bisphosphonate compound zoledronic acid (ZOL) within its central aqueous reservoir, while the exterior boundary is functionalized with specific asparagine-glycine-arginine (NGR) peptide ligands covalently linked to polyethylene glycol (PEG) polymer anchors. This surface modification alters the overall surface topography, membrane packing density, and surface charge profile. The resulting vesicles exhibit high colloidal stability and provide a defined model for peptide-surface interaction assays in cell-free environments.
Source
Custom synthesis
Functional Group
NGR peptide; Zoledronic acid
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
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