Properties
Description
NOTA-functionalized xylan derivatives exemplify radiometal chelation on carbohydrate platforms, utilizing β-xylose hydroxyls for stable ligand attachment while maintaining macrocycle's metal coordination geometry.
Glycan Structure
Its glycan structure is a linear backbone of β-1,4-linked D-xylose residues with side-chain substitutions including α-linked arabinofuranose, glucuronic acid/4-O-methyl-glucuronic acid, and acetyl groups at O-2 or O-3 positions.
Source
Chemical synthesis
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Xylan-NOTA can be used for its potential to develop NOTA-functionalized probes for positron emission tomography ligand development.
