Cat. No.: X23-10-ZQ078
p53 activator Tenovin-6, Purity ≥98%
Synonym: Tenovin-6; 1011557-82-6; Tenovin 6; 4-tert-Butyl-N-[[4-[5-(dimethylamino)pentanoylamino]phenyl]carbamothioyl]benzamide; p53 activator
- MDL: MFCD11976906
- CAS Number: 1011557-82-6
- Compound CID: 24772043
Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
Tenovin-6, soluble in DMSO and warmed water and insoluble in ethanol, is a potent and selective p53-activating compound. It targets p53, SIRT2, SIRT1, and SIRT3.
Molecular Formula
C25H34N4O2S
Targets
p53; SIRT2: 10 μM; SIRT1: 21 μM; SIRT3: 63 μM
Solubility
DMSO: 87 mg/mL (191.36 mM); Warmed water: 87 mg/mL (191.36 mM); Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Tenovin-6 can be used to activate p53 and inhibit sirtuins, providing a tool for research into cancer therapies.
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