Properties
Description
Paclitaxel-xylan conjugation creates a chemotherapeutic composite combining taxane properties with xylan's β-1,4-xylose scaffold from renewable resources. This system benefits from the polysaccharide's solubility-enhancing polymer network and biodegradation pathway.
Glycan Structure
Its glycan structure is a linear backbone of β-1,4-linked D-xylose residues with side-chain substitutions including α-linked arabinofuranose, glucuronic acid/4-O-methyl-glucuronic acid, and acetyl groups at O-2 or O-3 positions.
Source
Chemical synthesis
Functional Group
Paclitaxel
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Xylan-paclitaxel can be used for its potential to enhance hydrogel crosslinking through hydroxyl-rich amino acid modifications.
