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Paclitaxel stealth liposomes
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Cat. No.: X26-05-ZQ1678

Paclitaxel stealth liposomes

Synonym: Paclitaxel stealth LPs; PEGylated paclitaxel liposomes; Paclitaxel long-circulating liposomes

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Product Size
100 mg; 250 mg; 500 mg; 1 g; 5 g
Price
Datasheet
MSDS
Properties
Description
This formulation represents paclitaxel stealth liposomes designed to stabilize and solubilize a highly hydrophobic taxane diterpenoid compound within a sterically stabilized framework. The structural framework consists of a phosphatidylcholine lipid bilayer modified with polyethylene glycol conjugated lipids that accommodates the active paclitaxel molecule directly within its interior lipophilic hydrocarbon core. This configuration introduces a dense hydrophilic steric layer on the outer boundary that prevents physical vesicle aggregation and controls the passive crystallization of the taxane chains in open aqueous suspension. The resulting vesicles exhibit high colloidal stability and a narrow sub-micron size distribution profile.
Source
Custom synthesis
Functional Group
Paclitaxel
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Publications
Publications (0)

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