Properties
Description
PAE-chondroitin sulfate block copolymer is synthesized via ring-opening polymerization, alternating 尾-amino ester segments with chondroitin sulfate domains for pH-responsive behavior.
Glycan Name
Chondroitin sulfate
Glycan Structure
The glycan structure of chondroitin sulfate (CS) is a sulfated glycosaminoglycan (GAG) composed of repeating disaccharide units. Each unit consists of:
N-acetyl-D-galactosamine (GalNAc) (β1→4 linked)
D-glucuronic acid (GlcA) (β1→29 linked)
Source
Chemical synthesis
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Chondroitin sulfate-poly(β-amino ester) can be used for its potential to design biodegradable polyesters for gene delivery vector stabilization.
