Cat. No.: X24-09-YM615
PAI-1 inhibitor, Tiplaxtinin, Purity ≥98%
Synonym: 393105-53-8; PAI-039; Tiplasinin; PAI 039; Tiplasinin; 2-[1-Benzyl-5-[4-(trifluoromethoxy)phenyl]indol-3-yl]-2-oxoacetic acid; PAI-1 inhibitor
- MDL: MFCD09475615
- CAS Number: 393105-53-8
- Compound CID: 6450819
Product Size
5 mg; 10 mg; 25 mg; 50 mg
Properties
Description
Tiplaxtinin, soluble in DMSO and ethanol and insoluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting PAI-1. The molecular weight of the compound is 439.3833, and its molecular formula is C24H16F3NO4. It targets the PAI-1.
Molecular Weight
439.3833
Molecular Formula
C24H16F3NO4
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 62 mg/mL (141.1 mM); Water: insoluble; Ethanol (warmed): 15 mg/mL (34.13 mM); In vivo: 2.0% Tween 80 + 0.5% methylcellulose, 28 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
Tiplaxtinin can be studied extensively for its potential therapeutic applications in the treatment of metabolic disorders, including obesity and type 2 diabetes, by reducing lipid biosynthesis.
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