Lentinan-polyamidoamine, termed PAMAM-lentinan, constitutes a progressive molecular hybrid merging the immunomodulatory β-1,3-1,6-glucan lentinan with PAMAM. This hybrid structure leverages lentinan's helical tertiary architecture and anti-tumor potential through thymic-mediated immune response activation pathways.
Glycan Name
Lentinan
Glycan Structure
Its glycan structure is a β-(1→3)-linked d-glucose backbone with β-(1→6)-glucosyl side branches.
Source
Chemical synthesis
Functional Group
PAMAM
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Lentinan-polyamidoamine can be used for its potential to design PAMAM dendrimer complexes for multi-valent ligand presentation in pathogen binding inhibition.
Publications
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Publications
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