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PARP inhibitor A-966492, Purity ≥98%
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Cat. No.: X23-10-ZQ243

PARP inhibitor A-966492, Purity ≥98%

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Synonym: 934162-61-5; A966492; A-966492; 2-[2-Fluoro-4-[(2S)-2-pyrrolidinyl]phenyl]-1H-benzimidazole-7-carboxamide; PARP inhibitor

  • MDL: MFCD17215207
  • CAS Number: 934162-61-5
  • Compound CID: 16666333
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
A-966492, soluble in warmed DMSO and insoluble in water and ethanol, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks. It targets PARP1, PARP1, and PARP2.
Molecular Weight
324.4
Molecular Formula
C18H17FN4O
Targets
PARP1: 1 nM (Ki); PARP1: 1 nM (EC50); PARP2: 1.5 nM (Ki)
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 60 mg/mL (184.98 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
A-966492 can be used to explore its potential as a PARP inhibitor.
Publications
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