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PARP inhibitor AG-014699, Purity ≥98%

Cat. No.: X23-10-ZQ228

PARP inhibitor AG-014699, Purity ≥98%

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Synonym: 459868-92-9; Rucaparib phosphate; AG-014699; PF-01367338; AG014699; AG 014699; Rucaparib (phosphate); PARP inhibitor

  • MDL: MFCD17010269
  • CAS Number: 459868-92-9
  • Compound CID: 9931953
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AG-014699, soluble in DMSO and insoluble in ethanol and water, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks. It targets PARP.
Molecular Weight
421.4
Molecular Formula
C19H18FN3O.H3PO4
Targets
PARP: 1.4 nM (Ki)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 81 mg/mL (192.23 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
AG-014699 can be used to explore its potential as a PARP inhibitor in enhancing chemotherapy.
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