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PARP inhibitor AG14361, Purity ≥98%
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Cat. No.: X23-10-ZQ227

PARP inhibitor AG14361, Purity ≥98%

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Synonym: 328543-09-5; AG14361; AG-14361; AG 14361; Imidazo[4,5,1-jk][1,4]benzodiazepin-7(4H)-one, 2-[4-[(dimethylamino)methyl]phenyl]-5,6-dihydro-; 1-(4-((Dimethylamino)methyl)phenyl)-8,9-dihydro-2,7,9a-triazabenzo[cd]azulen-6(7H)-one; PARP inhibitor

  • MDL: MFCD18385009
  • CAS Number: 328543-09-5
  • Compound CID: 9840076
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AG14361, soluble in DMSO and insoluble in ethanol and water, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks. It targets PARP1.
Molecular Weight
320.4
Molecular Formula
C19H20N4O
Targets
PARP1: <5 nM (Ki)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 11 mg/mL (34.33 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
AG14361 can be used to study the role of PARP inhibition in enhancing radiosensitivity in cancer cells.
Publications
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