Cat. No.: X23-10-ZQ232
PARP inhibitor ME0328, Purity ≥98%
Synonym: 1445251-22-8; ME0328; ME-0328; 3-(4-oxo-3,4-Dihydroquinazolin-2-Yl)-N-[(1S)-1-phenylethyl]propanamide; (S)-3-(4-oxo-3,4-Dihydroquinazolin-2-yl)-N-(1-phenylethyl)propanamide; 3-(4-oxo-3H-QUINAZOLIN-2-YL)-N-[(1S)-1-PHENYLETHYL]PROPANAMIDE; PARP inhibitor
- CAS Number: 1445251-22-8
- Compound CID: 135566764
Product Size
25 mg; 50 mg; 100 mg
Properties
Description
ME0328, soluble in DMSO and insoluble in ethanol and water, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks. It targets PARP3 and PARP1.
Molecular Formula
C19H19N3O2
Targets
PARP3: 0.89 μM; PARP1: 6.3 μM
Solubility
DMSO: 60 mg/mL (186.69 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
ME0328 can be used to explore its potential as a proteasome inhibitor in cancer research.
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