Cat. No.: X23-10-ZQ206
PARP inhibitor NVP-TNKS656, Purity ≥98%
Synonym: 1419949-20-4; NVP-TNKS656; TNKS656; TNKS-656; N-(Cyclopropylmethyl)-2-(4-(4-methoxybenzoyl)piperidin-1-yl)-N-((4-oxo-3,5,7,8-tetrahydro-4H-pyrano[4,3-d]pyrimidin-2-yl)methyl)acetamide; PARP inhibitor
- CAS Number: 1419949-20-4
- Compound CID: 136237316
Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
NVP-TNKS656, soluble in DMSO and warmed ethanol and insoluble in water, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks.
Molecular Formula
C27H34N4O5
Solubility
DMSO: 89 mg/mL (179.95 mM); Water: Insoluble; Warmed ethanol: 9 mg/mL (18.19 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
NVP-TNKS656 can be used to inhibit tankyrase, providing insights into the regulation of Wnt signaling.
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