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PARP inhibitor NVP-TNKS656, Purity ≥98%
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Cat. No.: X23-10-ZQ206

PARP inhibitor NVP-TNKS656, Purity ≥98%

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Synonym: 1419949-20-4; NVP-TNKS656; TNKS656; TNKS-656; N-(Cyclopropylmethyl)-2-(4-(4-methoxybenzoyl)piperidin-1-yl)-N-((4-oxo-3,5,7,8-tetrahydro-4H-pyrano[4,3-d]pyrimidin-2-yl)methyl)acetamide; PARP inhibitor

  • CAS Number: 1419949-20-4
  • Compound CID: 136237316
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
NVP-TNKS656, soluble in DMSO and warmed ethanol and insoluble in water, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks.
Molecular Weight
494.58
Molecular Formula
C27H34N4O5
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 89 mg/mL (179.95 mM); Water: Insoluble; Warmed ethanol: 9 mg/mL (18.19 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
NVP-TNKS656 can be used to inhibit tankyrase, providing insights into the regulation of Wnt signaling.
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