Cat. No.: X23-10-ZQ238
PARP inhibitor UPF 1069, Purity ≥98%
Synonym: 1048371-03-4; UPF 1069; UPF-1069; 5-(2-oxo-2-Phenylethoxy)isoquinolin-1(2H)-one; 5-Phenacyloxy-2H-isoquinolin-1-one; PARP inhibitor
- MDL: MFCD14051631
- CAS Number: 1048371-03-4
- Compound CID: 25015515
Product Size
10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
UPF 1069, soluble in DMSO and insoluble in ethanol and water, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks. It targets PARP2 and PARP1.
Molecular Formula
C17H13NO3
Targets
PARP2: 0.3 μM; PARP1: 8.0 μM
Solubility
DMSO: 54 mg/mL (193.34 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
UPF 1069 can be used to investigate its function as a PARP inhibitor in neuroprotection.
Related Products
Quick Links