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PDE inhibitor, Cilomilast, Purity ≥98%

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Cat. No.: X24-08-YM476

PDE inhibitor, Cilomilast, Purity ≥98%

Synonym: 153259-65-5; SB207499; Ariflo; SB-207; 499; 4-Cyano-4-(3-cyclopentyloxy-4-methoxyphenyl)cyclohexane-1-carboxylic acid

CAS Number: 153259-65-5
Compound CID: 151170

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

Cilomilast, soluble in DMSO and ethanol and insoluble in water, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting PDE. It targets the HPDE4 and LPDE4.

Molecular Weight

343.4

Molecular Formula

C₂₀H₂₅NO₄

Targets

HPDE4: 120 nM (IC₅₀); LPDE4: 100 nM (IC₅₀)

Form

Lyophilized powder

Purity

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 64 mg/mL (186.36 mM); Water: insoluble; Ethanol: 47 mg/mL (136.85 mM); In vivo: 5% DMSO + 95% Corn oil, 28 mg/mL

Applications

Cilomilast is a metabolism inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of chronic obstructive pulmonary disease (COPD) and asthma.

Publications

Publications (0)

Publications

Publications

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