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PDE inhibitor, Cilomilast, Purity ≥98%
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Cat. No.: X24-08-YM476

PDE inhibitor, Cilomilast, Purity ≥98%

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Synonym: 153259-65-5; SB207499; Ariflo; SB-207; 499; 4-Cyano-4-(3-cyclopentyloxy-4-methoxyphenyl)cyclohexane-1-carboxylic acid

  • CAS Number: 153259-65-5
  • Compound CID: 151170
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Cilomilast, soluble in DMSO and ethanol and insoluble in water, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting PDE. It targets the HPDE4 and LPDE4.
Molecular Weight
343.4
Molecular Formula
C20H25NO4
Targets
HPDE4: 120 nM (IC50); LPDE4: 100 nM (IC50)
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 64 mg/mL (186.36 mM); Water: insoluble; Ethanol: 47 mg/mL (136.85 mM); In vivo: 5% DMSO + 95% Corn oil, 28 mg/mL
Applications
Cilomilast is a metabolism inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of chronic obstructive pulmonary disease (COPD) and asthma.
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