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PEG-modified docetaxel long-circulating liposomes

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Cat. No.: X26-05-ZQ2875

PEG-modified docetaxel long-circulating liposomes

Name: PEG-modified docetaxel long-circulating liposomes
SKU: X26-05-ZQ2875

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Synonym: PEG-modified DTX stealth LPs; PEGylated docetaxel long-circulating liposomes; PEG-modified docetaxel long-circulating LPs

Product Size

100 mg; 250 mg; 500 mg; 1 g; 5 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

This high-purity synthetic steric formulation features polyethylene glycol modified and docetaxel loaded long-circulating liposomes. The vesicular anatomy consists of a high-purity phospholipid-cholesterol bilayer shell whose exterior boundary is surface-modified with a dense layer (typically 5 mol%) of polyethylene glycol (PEG) polymer brushes, encapsulating the highly hydrophobic taxane derivative docetaxel directly within the lipophilic hydrocarbon tail regions of the bilayer shell. This precise configuration couples an optimized taxane matrix with a dense protective hydrophilic steric brush layer, altering overall membrane bending elasticity and surface hydration parameters to completely prevent physical vesicle aggregation and suppress docetaxel crystallization under ambient laboratory conditions.

Source

Custom synthesis

Functional Group

Docetaxel

Form

Solid or powder

Purity

≥95%

Impurities

No visible impurities to the naked eye.

Identity

HPLC/MS/NMR

Publications

Publications (0)

Publications

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Publications

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