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Peptide K237-modified paclitaxel thermosensitive liposomes
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Cat. No.: X26-05-ZQ2638

Peptide K237-modified paclitaxel thermosensitive liposomes

Synonym: Peptide K237-modified PTX thermosensitive LPs; K237 peptide-functionalized paclitaxel thermosensitive liposomes; Peptide K237-modified PTX temperature-sensitive liposomes

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Product Size
100 mg; 250 mg; 500 mg; 1 g; 5 g
Price
Datasheet
MSDS
Properties
Description
This advanced engineered responsive formulation features K237 peptide functionalized and paclitaxel loaded thermosensitive liposomes. The structural matrix incorporates a phase-transition lipid base composed primarily of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine designed to undergo a sharp melting transition at a specific thermal threshold (41ºC), encapsulating the hydrophobic diterpenoid paclitaxel within its lipid bilayer shell while its exterior boundary is surface-modified with specific K237 peptides. This specific configuration couples a thermally triggered release mechanism with a dense target-mimetic ligand array, completely preventing physical vesicle aggregation while suppressing taxane crystallization under baseline laboratory calibration indices.
Source
Custom synthesis
Functional Group
Peptide K237; Paclitaxel; Thermosensitive matrix
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Publications
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