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PFKFB3 inhibitor, 3PO, Purity ≥98%
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Cat. No.: X24-09-YM586

PFKFB3 inhibitor, 3PO, Purity ≥98%

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Synonym: 13309-08-5; 18550-98-6; 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one; (E)-3PO; (E)-3-Pyridin-3-yl-1-pyridin-4-ylprop-2-en-1-one; (E)-3-Pyridin-3-yl-1-pyridin-4-ylprop-2-en-1-one; PFKFB3 inhibitor

  • CAS Number: 13309-08-5; 18550-98-6
  • Compound CID: 5720233
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Product Size
25 mg; 50 mg; 100 mg; 200 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
3PO, soluble in DMSO and ethanol and insoluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting PFKFB3. The molecular weight of the compound is 210.24, and its molecular formula is C13H10N2O.
Molecular Weight
210.24
Molecular Formula
C13H10N2O
Form
Lyophilized powder
Purity
≥98%
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 39 mg/mL (185.51 mM); Water: insoluble; Ethanol: 39 mg/mL; In vivo: 2% DMSO + 40% PEG 300 + 2% Tween 80 + ddH2O, 1 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
3PO displays the significant potential to act as an effective inhibitor of AMP-activated protein kinase (AMPK), impacting metabolic pathways related to energy regulation.
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