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This high-purity synthetic model formulation features phosphatidic acid and cardiolipin multi-anionic liposomes (Phosphatidic acid and cardiolipin anionic liposomes (PA/CL LPs)). The vesicular matrix self-assembles from a precise molecular blend of the di-anionic, four-acyl-chain phospholipid cardiolipin (CL) and the mono-anionic phospholipid phosphatidic acid (PA) combined with neutral phosphatidylcholine helper lipids. This specialized lipid composition establishes an exceptionally dense negative surface charge topography and strong electrostatic repulsive forces, mimicking the high-curvature, highly charged inner mitochondrial membrane to provide an advanced model for studying divalent cation binding and lipid-lipid phase separation.
Source
Custom synthesis
Functional Group
Phosphatidic acid; Cardiolipin; Anionic matrix
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Publications
Publications (0)
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Publications
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CD BioGlyco is a leading biotechnology company specializing in glycobiology. We deliver high-quality products and services to support cutting-edge research worldwide.