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Phospholipase inhibitor, Darapladib, Purity ≥98%
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Cat. No.: X24-09-YM418

Phospholipase inhibitor, Darapladib, Purity ≥98%

Synonym: 356057-34-6; SB-480848; SB 480848; SB480848; N-[2-(Diethylamino)ethyl]-2-[2-[(4-fluorophenyl)methylsulfanyl]-4-oxo-6,7-dihydro-5H-cyclopenta[d]pyrimidin-1-yl]-N-[[4-[4-(trifluoromethyl)phenyl]phenyl]methyl]acetamide; Phospholipase inhibitor

  • MDL: MFCD18251452
  • CAS Number: 356057-34-6
  • Compound CID: 9939609
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
MSDS
Properties
Description
Darapladib, soluble in DMSO and ethanol and insoluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting phospholipases. The molecular weight of the compound is 666.77, and its molecular formula is C36H38F4N4O2S. It targets the Lp-PLA2.
Molecular Weight
666.77
Molecular Formula
C36H38F4N4O2S
Targets
Lp-PLA2
Form
Lyophilized powder
Purity
≥98%
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO (warmed): 96 mg/mL (143.97 mM); Water: insoluble; Ethanol: 96 mg/mL (143.97 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Darapladib can be used for its potential to reduce cardiovascular events by targeting the inflammatory component of atherosclerosis.
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