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Phospholipase inhibitor, Darapladib, Purity ≥98%

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Cat. No.: X24-09-YM418

Phospholipase inhibitor, Darapladib, Purity ≥98%

Synonym: 356057-34-6; SB-480848; SB 480848; SB480848; N-[2-(Diethylamino)ethyl]-2-[2-[(4-fluorophenyl)methylsulfanyl]-4-oxo-6,7-dihydro-5H-cyclopenta[d]pyrimidin-1-yl]-N-[[4-[4-(trifluoromethyl)phenyl]phenyl]methyl]acetamide; Phospholipase inhibitor

MDL: MFCD18251452
CAS Number: 356057-34-6
Compound CID: 9939609

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

Darapladib, soluble in DMSO and ethanol and insoluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting phospholipases. The molecular weight of the compound is 666.77, and its molecular formula is C₃₆H₃₈F₄N₄O₂S. It targets the Lp-PLA2.

Molecular Weight

666.77

Molecular Formula

C₃₆H₃₈F₄N₄O₂S

Targets

Lp-PLA2

Form

Lyophilized powder

Purity

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO (warmed): 96 mg/mL (143.97 mM); Water: insoluble; Ethanol: 96 mg/mL (143.97 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

Darapladib can be used for its potential to reduce cardiovascular events by targeting the inflammatory component of atherosclerosis.

Publications

Publications (0)

Publications

Publications

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