Cat. No.: X23-10-ZQ438
Pim inhibitor AZD1208, Purity ≥98%
Synonym: AZD1208; 1204144-28-4; AZD-1208; (R,Z)-5-((2-(3-Aminopiperidin-1-yl)-[1,1'-biphenyl]-3-yl)methylene)thiazolidine-2,4-dione; S98NFM1378; UNII-S98NFM1378; (5Z)-5-({2-[(3R)-3-Aminopiperidin-1-yl]-3-phenylphenyl}methylidene)-1,3-thiazolidine-2,4-dione; Pim inhibitor
- MDL: MFCD25976757
- CAS Number: 1204144-28-4
- Compound CID: 58423153
Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
AZD1208, soluble in warmed DMSO and insoluble in water and ethanol, is a selective and ATP-competitive Pim kinase inhibitor. It targets Pim1, Pim2, and Pim3.
Molecular Formula
C21H21N3O2S
Targets
Pim1: 0.4 nM; Pim2: 5 nM; Pim3: 1.9 nM
Solubility
Warmed DMSO: 70 mg/mL (184.45 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
AZD1208 can be utilized to investigate PIM kinase inhibition, focusing on its anti-cancer properties.
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