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PLK inhibitor Mps1-IN-2, Purity ≥98%
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Cat. No.: X24-05-ZQ847

PLK inhibitor Mps1-IN-2, Purity ≥98%

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Synonym: 1228817-38-6; Mps1-IN-2; 9-Cyclopentyl-2-[2-ethoxy-4-(4-hydroxypiperidin-1-yl)anilino]-5-methyl-7,8-dihydropyrimido[4,5-b][1,4]diazepin-6-one; PLK inhibitor

  • CAS Number: 1228817-38-6
  • Compound CID: 44968267
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Mps1-IN-2 targets Polo-like kinases, which are essential regulators of cell division and mitosis, making them effective in halting the proliferation of cancer cells. It targets GAK, Mps1, PLK1, and PLK3.
Molecular Weight
480.6
Molecular Formula
C26H36N6O3
Targets
GAK: 140 nM (Kd); Mps1: 12 nM (Kd); PLK1: 61 nM (Kd); PLK3: 1600 nM (Kd)
Form
Lyophilized powder
Purity
≥98%
Identity
Confirmed by NMR/HPLC/MS.
Applications
Mps1-IN-2 is used to study its role in inhibiting monopolar spindle 1 kinase and its effects on chromosome segregation.
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