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Cat. No.: X23-12-YM759

Ponesimod

Synonym: 854107-55-4; ACT-128800

  • CAS Number: 854107-55-4
  • Compound CID: 11363176
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
MSDS
Properties
Description
Ponesimod, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets S1P1 receptor.
Molecular Weight
460.97
Molecular Formula
C23H25ClN2O4S
Targets
S1P1 receptor: 5.7 nM (EC50)
Form
Lyophilized powder
Purity
>98%
Solubility
DMSO: 82 mg/mL (177.88 mM); Water: insoluble; Ethanol: 82 mg/mL
Applications
Ponesimod can be used for its ability to retain certain white blood cells (lymphocytes) within the lymph nodes, thereby preventing their migration into the central nervous system where they can contribute to inflammation and damage.
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