Ponesimod, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets S1P1 receptor.
Ponesimod can be used for its ability to retain certain white blood cells (lymphocytes) within the lymph nodes, thereby preventing their migration into the central nervous system where they can contribute to inflammation and damage.
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