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PPAR inhibitor, BMS-687453, Purity ≥98%
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Cat. No.: X24-08-YM444

PPAR inhibitor, BMS-687453, Purity ≥98%

Synonym: 1000998-59-3; BMS687453; BMS 687453; 2-[[3-[[2-(4-Chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methoxy]phenyl]methyl-methoxycarbonylamino]acetic acid

  • MDL: MFCD18251482
  • CAS Number: 1000998-59-3
  • Compound CID: 16725047
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
MSDS
Properties
Description
BMS-687453, soluble in DMSO and ethanol and insoluble in water, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting PPAR. It targets the PPARα.
Molecular Weight
444.86
Molecular Formula
C22H21ClN2O6
Targets
PPARα: 260 nM (IC50, human PPARα)
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 80 mg/mL (179.83 mM); Water: insoluble; Ethanol: 80 mg/mL
Applications
BMS-687453 is a metabolism inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of type 2 diabetes by improving insulin sensitivity and glucose homeostasis.
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