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Proteasome inhibitor MLN2238, Purity ≥98%
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Cat. No.: X24-07-ZQ700

Proteasome inhibitor MLN2238, Purity ≥98%

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Synonym: 1072833-77-2; Proteasome inhibitor; MLN 2238; MLN-2238

  • MDL: MFCD18251438
  • CAS Number: 1072833-77-2
  • Compound CID: 25183872
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
MLN2238, soluble in DMSO and ethanol and insoluble in water, interferes with the proteasome’s ability to degrade proteins, thereby disrupting cellular processes in cancer cells, particularly multiple myeloma. It targets 20S proteasome and 20S proteasome.
Molecular Weight
361
Molecular Formula
C14H19BCl2N2O4
Targets
20S proteasome: 0.93 nM (Ki); 20S proteasome: 3.4 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 64 mg/mL (177.26 mM); Water: Insoluble; Ethanol: 8 mg/mL (22.15 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
MLN2238 is utilized to investigate and inhibit proteasomes, which play a crucial role in degrading ubiquitinated proteins, and are involved in cancer research.
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